Reuters Published April 22, 2026 Updated 13 minutes ago NEW YORK: Wall Street’s main indexes were subdued on Tuesday, as renewed concerns about the Middle East war halted an early rally in stocks and overshadowed earnings optimism. Pakistan is still awaiting a formal response from Iran to confirm that it will send a delegation to attend a second round of peace talks with the US in Islamabad, the country’s Information Minister Attaullah Tarar said in a post on X. The talks are scheduled against a fragile backdrop. In an interview with CNBC earlier, US President Donald Trump said he does not want to extend the ceasefire with Iran, which is set to expire soon. A failure to resume the discussions could swiftly upend investors’ assumptions that peak uncertainty related to the war has passed. At 11:52 a.m. ET, the Dow Jones Industrial Average fell 87.88 points, or 0.18 percent, to 49,354.68, the S&P 500 lost 19.21 points, or 0.27 percent, to 7,089.93 and the Nasdaq Composite slipped 38.08 points, or 0.16 percent, to 24,366.32. All the indexes were in positive territory earlier in the session. Investors are also parsing comments from Kevin Warsh, Trump’s nominee to lead the Federal Reserve, whose confirmation hearing was underway in the Senate on Tuesday. He called for “regime change” at the US central bank that would include a new “framework” for controlling inflation and a possible…